Chimeric antigen receptor (CAR)-T cell therapy shows excellent potency against hematological malignancies, but it remains challenging to treat solid tumors, mainly because of a lack of appropriate musta lautanen antigenic targets and an immunosuppressive tumor microenvironment (TME).The checkpoint molecule programmed death-ligand 1 (PD-L1) is widel
Silver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells
Daoud Ali, Saud Alarifi, Saad Alkahtani, Rafa S Almeer Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia Introduction: Graphene oxide nanoparticles have been widely used in industry and biomedical fields due to their unique physicochemical properties.However, comparative cytotoxicity of silver-doped reduced graph
The Power of Proof In Victims of Sexsual Abuse
Introduction: Enforcement and legal protection e1504ga-ws34 for sexual assault cases has focused on protecting the victims of sexual assault law which consists of physical or psychological violence, retaliation, humiliation, and mistreatment of people who support victims of violence against women in particular.Where the focus of this tuilsan mebaha
Changing approaches to financing and financial management in the South African local government sector
Sections 152 and 153 of the Constitution of the Republic of South Africa, 1996 (Act 108 of 1996) have given local government a developmental mandate.Local government has a constitutional obligation to participate in national and provincial development programmes.Local government should become a powerful development catalyst in kotha model dress col